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Furthermore, SIRT1 regulates T-cell-mediated immunity by preventing CD4 + T cells from differentiating into interleukin-9-secreting cells and downregulating transcription factors like NF-κB and AP-1, crucial for regulating T-cell responses [80]

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For example, the role of industry interference with the scientific process, long known to be a significant inhibitor to progress in the field of science, 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 was not probed systematically in this study