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Abbreviations ADH alcohol dehydrogenase AH alcoholic hepatitis ALD alcohol-related liver diseases ALDH aldehyde dehydrogenase ASH alcoholic steatohepatitis CAT catalase CD14 cluster of differentiation 14 CI confidence interval CYP2E1 cytochrome P450 2E1 HCC hepatocellular carcinoma HR hazard ratio iNOS inducible nitric oxide synthase LTA lipoteichoic acid NAD + nicotinamide adenine dinucleotide NF-κB nuclear factor-κB PAMPs pathogen-associated molecular patterns ROS reactive oxygen species RR relative risk TLR toll-like receptor TNF tumor necrosis factor Funding Funded in parts by grants from the Austrian Science Fund (FWF, [P-32164] to IB) and the Wissenschaftsförderung der Deutschen Brauwirtschaft e.V