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Similar results were reported by Uzel et al (1987) [12], Gallow et al (1993) [13], Ayden (2001) [14] and Seghrolchni et al (2002) [15] in type II DM patients

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An animal study revealed that when DSIP was directly injected into the bulbo-mesencephalo-thalamic recruitment system, it induced slow-wave sleep and Naloxone-reversed sleep spindle activity