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Molecular Mechanisms and Risk Factors Related to the Pathogenesis of Peyronie's Disease

Figure 3g depicted that the mutant S37A is sufficient to mimicking U0126 or ERK2 siRNA for perturbing the ability of hypoxia to phosphorylate 14-3-3ζ because 14-3-3ζ S37A failed to undergo phosphorylation to the same extent as its wild-type counterpart did under hypoxia, and even so, ERK2 was able to phosphorylate the wild-type 14-3-3ζ but not the mutant 14-3-3ζ S37A (Fig

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Pflaum, T