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1–22), three new butyrolactones (1–3) and three butanates (4–6), or taraxioside A-F (Figure 3) (1) 1,2,5-tri-O-p-hydroxyphenylacetyl-L-chiro-inositol, (2) chrysoeriol, (3) 5,7,30-hydroxy-40,50-dimethoxy flavone, (4) methyl 3,4-dihydroxycinnamate, (5) 5,7,40-hydroxy-30,50-dimethoxy flavone, (6) luteolin, (7) 3-glycerindole, (8) calquiqueignan D, (9) calquiquelignan E, (10) tricin 40-O-[threo-b-guaiacyl-(700-Omethyl)-glyceryl] ether, (11) tricin 40-O-[erythro-b-guaiacyl-(700-O-methyl)-glyceryl] ether, (12) loliolide, (13) epiloliolide, (14) annuionone, (15) 11b,13-dihydrotaraxinic acid b-O-glucopyranoside, (16) 3,4-dihydroxy-5,7-megastigmadien-9-one, (17) komaroveside A, (18) 6S,9R-roseoside, (19) 6S,9S-roseoside, (20) adenosine, (21) aesculetin-7-O-b-D-glucopyranoside, and (22) syringin
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FOS has been shown to ameliorate DN by improving gut dysbiosis and inflammation (Pengrattanachot et al., 2022)