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In TME, higher levels of milk fat globule-epidermal growth factor 8 (MFGE8) promote efferocytosis by stimulating macrophages to remove cisplatin-induced apoptotic cells, contributing to the lethal consequences of chemotherapeutic resistance (Ma et al., 2024)

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developed a safe mitochondria-targeted copper-depleting nanoparticle (CDN) and tested it against triple-negative breast cancer (TNBC)