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All these molecules increase vascular permeability and recruit inflammatory cells [31]

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Based on this, we proposed to include a family update as part of the plan when the patient is admitted (write in the admission clerking) to do it in the first 6 hours after admission, to include a tick box in the ward round proforma about family update to remind the doctors about it, document in the ward round notes the specifics of what to discuss with the relatives, for very ill patients, schedule the routine phone calls to avoid missing it and ensure that all discussions/updates are documented in the green communication sheets