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These include interferon regulatory factor 4 (IRF4), Krüppel-like factor 11 (KLF11), TATA-binding protein associated factor 7L (TAF7L), zinc finger and BTB domain-containing protein 16 (ZBTB16), placenta-specific gene 8 protein (PLAC8), early B cell factor 2 (EBF2), forkhead box C2 (FoxC2) and ewing sarcoma break point region 1 (EWSR1) (Seale et al., 2009

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These investigations focus on pathway relationships, signaling dynamics, and system-level interactions rather than specific biological outcomes