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There is general agreement that M3 receptors are primarily responsible for the normal contraction of the urinary bladder , although M2 receptors are also present, and may act to oppose sympathetically mediated smooth muscle relaxation mediated by beta-3 receptors (Hedge, 2009

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Techniques for conjugating such therapeutic moiety to antibodies are well known, see, e.g., Arnon et al., “Monoclonal Antibodies For Immunotargeting Of Drugs In Cancer Therapy”, in Monoclonal Antibodies And Cancer Therapy, Reisfeld et al