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Note the almost total lack of vitamin B12 in the brain of the subject (Collins, 2019), similar data by Sah, et al, 2014) Absolute or functional vitamin B12 deficiency in the womb is associated with a higher incidence of Neural Tube Defects, and various oro-facial conditions such as Cleft Lip, Cleft Palate, and Tongue Tie, which may lead to difficulties in the baby breast-feeding (Weekes et al, 1992