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It was found that overexpression of GPX2 promotes proliferation and invasion, prevents the apoptosis of LNCaP and 22RV1 cells, and triggers the activation of the Wnt/β-catenin and epithelial–mesenchymal transition (EMT) pathways, which are related to the occurrence and development of prostate cancer [123]

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But however carefully this may be done, the sinuses are always so crooked or winding, that the first dressing can seldom be got to the bottom of them