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[DOI] [PubMed] [Google Scholar] 12.Cassiano D., Esposito A.C.C., Hassun K., Bagatin E., Lima M.M.D.A., Lima E.V.A., et al
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Studies looking at NR doses up to 2,000mg per day and NMN doses up to 1,200mg per day found no differences in adverse effects between intervention and placebo groups.31 4 In studies of higher doses that produced adverse effects, typical reactions included:32 Headache Dry mouth GI upset Muscle cramps or spasms As with many forms of vitamin B, NR can cause some flushing, and both NR and NMN can cause digestive upset
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