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Lastly, tell your doctor is you have ever suffered from: Liver or kidney conditions Cardiac issues, including recent heart attacks Blood clotting or bleeding disorders Epilepsy or seizure disorders Narrow-angle glaucoma Long QT syndrome Substance abuse or suicidal ideation Bipolar disorder (manic depression) Pregnancy Considerations There is limited data on the safety of trazodone in pregnant women, and its effects on the developing fetus are not fully understood