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Lifestyle Changes Even routine moderate exercise, which includes 150 minutes a week of mixed aerobic and resistance work, lowers both systemic inflammation and oxidative load

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4,11,15 Inflammatory responses mediated by proinflammatory cytokines and pathways, such as nuclear factor kappa B (NF-κB) and Toll-like receptor 4 (TLR4), worsen the condition by amplifying oxidative stress and hindering neuronal repair