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Because many age-related defects are linked to OxS (9–14), GlyNAC supplementation could play a novel role in improving/correcting age-associated abnormalities by lowering and correcting OxS

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The enclosed volume within the contours was measured, and the percent cortex of the cavity was calculated with the following formula: percentage of the cortical cavity = (contralateral cortex volume − ipsilateral spare cortex volume)/(contralateral cortex volume) × 100%