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What To Know About Vitamin B12 Vitamin B12, also called cobalamin, is a type of water-soluble vitamin and plays a vital role in several essential bodily processes

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Indeed, loss of GCH1, 6-pyruvoyl-tetrahydropterin synthase or sepiapterin reductase sensitize cancer cells to GPX4 inhibition [53] and overexpression of GCH1 is sufficient to increase resistance to Gpx4 loss and inhibition and imidazole ketone erastin (IKE) treatment [54]